Associate Researcher - 19212BR
The Protein Structure Laboratory (PSL) is a core laboratory that focuses on the 3-dimensional structure determination of proteins, using X-ray crystallography, for collaborators’ projects. As such, the PSL manages all tasks in the structure determination process including initial construct design, assistance with protein purification, crystallization, X-ray diffraction data collection, structure solution/refinement and structure analysis. The PSL Associate Researcher will be responsible for assisting with sample purification, setup and monitoring of all crystallization experiments, refinement of crystallization conditions, sample preparation for X-ray diffraction tests, documentation of experimental tasks and preparation of project reports. For further information please see http://psf.cobre.ku.edu/cores/psl/about.
The PSL Associate Researcher will carry out and manage all crystallization experiments and assist with sample preparation and analysis using X-ray diffraction methods for investigator’s research projects. This includes the monitoring and tracking of all crystallization screening experiments and devising experimental plans for crystal optimization. Additional responsibilities include assisting with protein purification, preparation of protein samples for crystallization experiments and analysis of protein sample quality.
15% - Laboratory supervising
Oversee the daily operations of the PSL crystallization laboratory. This includes maintaining the inventory of consumable supplies, preparing stock solutions for crystallization, general laboratory cleanliness, introducing users to the laboratory guidelines and providing training to users in the area of protein crystallization. Additional responsibilities include providing expert advice to the PSL Director regarding areas to improve/enhance the laboratory’s capabilities.
10% - Documentation/Analysis
Responsibilities include: 1) Preparation and analysis of scientific research materials for experiments performed in the PSL, 2) Devising research methods and plans for carrying out purification and crystallization experiments, 3) Maintaining detailed notes and records pertaining to all research work, 4) Writing detailed final reports for investigator’s projects and 5) In some cases co-author publications of research results.
5% - Training
Provide training to junior researchers such as graduate students and post-docs in the methods utilized for protein crystallization
2. A record of published, peer-reviewed research in areas related to the field of protein structure determination using X-ray crystallography.
Additional Candidate Instructions
Application review will begin on June 14, 2021 and will continue until a successful candidate is identified.